Dr. Xu of Baylor College of Medicine joins the podcast to share his latest work on how a particular brain circuit contributes to anorexia nervosa, the psychiatric disease characterized by fear of gaining weight and severe food restriction. Dr. Xu explains how dopamine and serotonin neurons in the brain regulate feeding behavior and often communicate with each other. Importantly, new research from his lab shows how the strength of that communication determined how much animals ate and exercised, thereby allowing researchers to elucidate the mechanisms underlying anorexia.
Paper Referenced in the Episode:
1. Cai et al., 2022: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice
Follow PictureBlurrfect on Social Media:
Twitter: @Blurrfect
Instagram: @picture_blurrfect
E-mail: naomi.charalambakis90@gmail.com
Dr. Xu of Baylor College of Medicine joins the podcast to share his latest work on how a particular brain circuit contributes to anorexia nervosa, the psychiatric disease characterized by fear of gaining weight and severe food restriction. Dr. Xu explains how dopamine and serotonin neurons in the brain regulate feeding behavior and often communicate with each other. Importantly, new research from his lab shows how the strength of that communication determined how much animals ate and exercised, thereby allowing researchers to elucidate the mechanisms underlying anorexia.
Paper Referenced in the Episode:
1. Cai et al., 2022: A D2 to D1 shift in dopaminergic inputs to midbrain 5-HT neurons causes anorexia in mice
Follow PictureBlurrfect on Social Media:
Twitter: @Blurrfect
Instagram: @picture_blurrfect
E-mail: naomi.charalambakis90@gmail.com